The second coalition agreement has now been published. I have it in a PDF form and it would be messy to simply copy the text into the weblog hence I am not publishing it here.
It is here.
It is here.
People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are caused by cells not being able to produce enough of the right proteins. What happens is that certain genes stop functioning because of a metabolic imbalance. I was, however, mystified as to why it was always particular genes that stopped working. Recently, however, there have been three papers produced: Aging is associated with a systemic length-associated transcriptome imbalance Age- or lifestyle-induced accumulation of genotoxicity is associated with a generalized shutdown of long gene transcription and Gene Size Matters: An Analysis of Gene Length in the Human Genome From these it is obvious to see that the genes that stop working are the longer ones. To me it is therefore obvious that if there is a shortage of nuclear Acetyl-CoA then it would mean that the probability of longer Genes being transcribed would be reduced to a greater extent than shorter ones.
Comments
I am deeply dissapointed though to know there's nothing contained within the agreement about the much needed overhaul of the Children's Services Dept, suppose we will have to wait another five years for someone to realise that the policies of the old Labour government simply do not work but cost the tax payer millions of wasted pounds a year.
Ideal time to take action but sadly this oppertunity has been missed.